Vitamin D3 99 +% extra pure, USP

Cholecalciferol (also abbreviated colecalciferol or calciol; vitamin D3 or incorrect vitamin D) is the useful physiological form of vitamin D in all non-vegetable eukaryotes and therefore also in humans. Cholecalciferol is a secosteroid and is also boosted in the body with the help of UVB radiation in the skin from 7-dehydrocholesterol.

In the diet it mainly occurs in oily fish or it is added to the feed as a dietary supplement. It has the function of a prohormone in the body and is represented through the intermediate calcidiol in its physiologically active form, the hormone calcitriol.

Cholecalciferol is a form of vitamin D that is naturally synthesized in the skin and functions as a prohormone and is displayed in calcitriol. This is important to maintain calcium levels and to modify bone health and development. As a medicine, cholecalciferol can be taken as a dietary supplement to prevent or treat vitamin D deficiency. One gram is 40,000,000 (40x106) IU, equivalent 1 IU is 0.025 µg. The dietary reference intakes for vitamin D (cholecalciferol and / or ergocalciferol) have been established and the recommendations depending on the country:

Low vitamin D levels are more commonly found in individuals living in the original race degrees, or for other reasons for minor to rapid exposure, such as being housebound, frail, elderly, obese, dark-skinned, or clothing which bears most of the skin covered. Supplements are recommended for these groups of people.

The Institute of Medicine recommended a maximum intake of vitamin D of 4,000 IU / day in 2010, finding that the dose for the lowest minimum adverse event level was 40,000 IU per day for at least 12 weeks, and there was a single case of toxicity above 10,000 IU after more than 7 years of daily intake; this case of toxicity occurred in circumstances that have placed other children in dispute as a plausible case to consider when making recommendations for vitamin D intake. Patients with severe vitamin D deficiency are on treatment with a loading dose required; its size can be calculated based on the actual serum 25-hydroxy vitamin D content and body weight.

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Gevarenaanduidingscode 

• H300 H310 + H330 Dodelijk bij inslikken, bij contact met de huid en bij inademing.
• H372 Veroorzaakt schade aan organen bij langdurige of herhaalde blootstelling bij inslikken.

Preventieve code

• P260 Stof/ rook/ gas/ nevel/ damp/ spuitnevel niet inademen.
• P262 Contact met de ogen, de huid of de kleding vermijden.
• P280 Draag beschermende handschoenen/ beschermende kleding.
• P302 + P352 + P310 BIJ CONTACT MET DE HUID: met veel water wassen. Onmiddellijk een ANTIGIFCENTRUM/ arts raadplegen.
• P304 + P340 + P310 NA INADEMING: de persoon in de frisse lucht brengen en ervoor zorgen dat deze gemakkelijk kan ademen. Onmiddellijk een ANTIGIFCENTRUM/ arts raadplegen.
• P314 Bij onwel voelen een arts raadplegen.