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n-hexane
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What is n-Hexane
N-hexane, or sometimes just hexane, is a saturated hydrocarbon of the alkane family with the crude formula C6H14.
What is n-Hexane used for?
Hexane is a solvent used in organic chemistry (especially for reactions and extractions). It is important to respect the safety rules regarding this compound due to its toxicity.
This is manifested by the formation of a metabolite, hexane-2,5-dione, a dicarbonyl compound, which accumulates in the central nervous system and is highly toxic. The latter can be measured in the urine to detect possible intoxication.
Hexane is therefore often replaced by cyclohexane, especially for preparative chromatography. If the use of hexane is preferred, it is advisable to protect yourself well, especially thanks to extractor hoods.
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Technical data
Empirical formula C6H14
Molar mass (M) 86.18 g/mol
Density (D) 0.66
Boiling point (bp) 69 °C
Flash point (flp)-26°C • Melting point (mp)-95°C
ADR 3 II • WGK 2
CAS No.[110-54-3]
EC-No. 203-777-6 • UN No. 1208
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Hazard Statements
H225 Highly flammable liquid and vapour
H304 May be fatal if swallowed and enters airways
H315 Causes skin irritation
H336 May cause drowsiness or dizziness
H361 Suspected of damaging fertility or the unborn child
H373 May cause damage to organs through prolonged or repeated exposure
H411 Toxic to aquatic life with long lasting effects
Precautions - Prevention
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. Do not smoke.
P243 Take precautions to avoid static discharges.
P273 Avoid release to the environment.
Precautions - Response
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor.
P331 DO NOT induce vomiting.
Precautions - Storage
P403+P235 Store in a well-ventilated place. Keep cool.
Additional Hazard Information
EUH066 Repeated exposure may cause skin dryness or cracking.